TianlaiChen
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README.md
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I agree to use this model for non-commercial use ONLY: checkbox
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**PepMLM: Target Sequence-Conditioned Generation of Peptide Binders via Masked Language Modeling**
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![image/png](https://cdn-uploads.huggingface.co/production/uploads/63df6223f351dc0745681f77/
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In this work, we introduce **PepMLM**, a purely target sequence-conditioned *de novo* generator of linear peptide binders.
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By employing a novel masking strategy that uniquely positions cognate peptide sequences at the terminus of target protein sequences,
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PepMLM tasks the state-of-the-art ESM-2 pLM to fully reconstruct the binder region,
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I agree to use this model for non-commercial use ONLY: checkbox
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---
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**PepMLM: Target Sequence-Conditioned Generation of Peptide Binders via Masked Language Modeling**
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![image/png](https://cdn-uploads.huggingface.co/production/uploads/63df6223f351dc0745681f77/hkKA0GttGY5l3oVcKf0bR.png)
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In this work, we introduce **PepMLM**, a purely target sequence-conditioned *de novo* generator of linear peptide binders.
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By employing a novel masking strategy that uniquely positions cognate peptide sequences at the terminus of target protein sequences,
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PepMLM tasks the state-of-the-art ESM-2 pLM to fully reconstruct the binder region,
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